Cu-ATSM and Cu-PTSM are classified as what type of PET agents?

Cu-ATSM and Cu-PTSM are classified as angiogenesis and cell proliferation tracers. These compounds are copper-based radiopharmaceuticals that play a significant role in evaluating hypoxic tumors due to their selective uptake in areas with low oxygen levels, which often correlate with enhanced angiogenesis and cellular proliferation. The ability of these agents to localize in tumor tissues makes them useful for assessing the aggressiveness of tumors and for evaluating therapeutic responses in oncological studies.

Although there are other categories of PET agents, Cu-ATSM and Cu-PTSM's primary function is linked to their involvement in processes associated with tumor growth and the formation of new blood vessels, thereby justifying their classification as angiogenesis and cell proliferation tracers.