In which part of the brain is the high uptake of FDG distribution observed?

The high uptake of FDG (fluorodeoxyglucose) in the brain is primarily observed in areas with high metabolic activity, which is often represented by high levels of glucose consumption. The basal ganglia are particularly significant in this context because they are involved in the regulation of voluntary motor control, procedural learning, and certain cognitive functions, all of which require a substantial amount of energy and, consequently, glucose.

In the basal ganglia, particularly regions like the putamen and caudate nucleus, there is a prominent PET signal due to the high metabolic rate associated with their functions. This characteristic makes the basal ganglia a key focus for various studies in neuroimaging, as observed in conditions like Parkinson's disease and other movement disorders.

While other areas of the brain such as the hippocampus also show notable FDG uptake due to their roles in memory and learning, the basal ganglia are typically recognized for their distinctly higher metabolic activity related to their extensive involvement in both motor and cognitive processes. The cerebellum does show metabolic activity, but in the context of high FDG uptake, it does not have as prominent a role as the basal ganglia. The medulla oblongata, being part of the brainstem, is primarily responsible