What compound is produced by nucleophilic substitution of mannose triflate?

In the context of synthesizing radiopharmaceuticals, specifically using mannose triflate, the correct compound produced by nucleophilic substitution is 18F-FDG, which stands for 18-fluoro-deoxyglucose. Nucleophilic substitution reactions involve the replacement of a leaving group in a compound by a nucleophile. In the case of mannose triflate, the triflate group acts as a good leaving group, allowing a nucleophile, such as a fluorine-18 ion, to substitute for it.

18F-FDG is particularly significant in PET imaging as it is a radiotracer that mimics glucose and is taken up by glucose-avid tissues, such as cancer cells. The incorporation of the radioactive fluorine-18 into the glucose structure is essential for the visualization of metabolic activity in tissues during PET scans.

The other choices do not represent the product of nucleophilic substitution in this context. Potassium carbonate is often used as a base in synthetic reactions but is not a product of the reaction with mannose triflate. The percentages provided do not refer to any relevant production yield in this case. Therefore, the correct answer directly relates to the use of mannose triflate in synthesizing radiolabeled compounds