What is a key symptom of Pick's disease?

Pick's disease, which is a form of frontotemporal dementia, is characterized by specific pathological changes in the brain, one of the most distinctive being the presence of Pick's bodies. These are abnormal aggregates of proteins found within the neurons and are a hallmark of the condition. Their identification is essential for diagnosis and is a defining feature that distinguishes Pick's disease from other neurodegenerative disorders.

While other symptoms may be present in patients with Pick's disease, such as changes in personality, social behavior, and impairment in judgment, the presence of Pick's bodies directly correlates with the underlying pathology of the disease and is crucial in confirming the diagnosis through histological examination. This is what makes the identification of Pick's bodies a key symptom tied specifically to Pick's disease.