What is the acceptable pH range for FDG?

FDG, or fluorodeoxyglucose, is a radiopharmaceutical widely used in PET imaging. The acceptable pH range for FDG is critical for maintaining the compound's stability and ensuring patient safety during administration.

A pH range of 4.5 to 7.5 is ideal for FDG because it allows the compound to remain in a stable condition, avoiding degradation that can occur at more acidic or basic pH levels. In this range, the FDG retains its chemical integrity and biological effectiveness, which is essential for accurate imaging results.

If the pH were to fall below 4.5, the increased acidity could lead to hydrolysis of the FDG, reducing its reliability and causing potential issues with patient safety. Conversely, if the pH exceeds 7.5, it could result in the instability of the compound, affecting imaging quality and the safety of the administered dosage.

Overall, maintaining the pH within the range of 4.5 to 7.5 ensures optimal performance of FDG in PET imaging protocols, making this choice the correct answer regarding the acceptable pH range for FDG.