What is the primary advantage of PET over SPECT in imaging?

The primary advantage of Positron Emission Tomography (PET) over Single Photon Emission Computed Tomography (SPECT) is its high sensitivity. This sensitivity allows PET scans to detect much lower concentrations of radiotracers, thus providing clearer and more detailed images of metabolic processes in tissues. PET achieves this by using radiotracers that emit positrons, which are then detected by the PET scanner to produce high-resolution images. The improved sensitivity of PET enables better visualization of biological processes at a molecular level, making it an invaluable tool in diagnosing and monitoring various conditions, particularly in oncology, cardiology, and neurology.

While cost, availability, and radiation exposure are important aspects to consider when comparing imaging modalities, they do not surpass the sensitivity advantage. Higher sensitivity in PET translates to more accurate diagnosis and better differentiation between normal and pathological conditions, ultimately enhancing patient care.