What is the typical percentage yield of 18F to 18F-FDG?

The typical percentage yield of 18F to 18F-FDG is generally in the range of 50-80%. This yield is largely influenced by the efficiency of the synthesis process and the purity of the precursors used. For instance, when synthesizing 18F-FDG from 18F, various factors such as reaction conditions, the quality of reagents, and the design of the production equipment can significantly impact the overall yield. Achieving yields within this range ensures that there is enough radiotracer available for clinical use while minimizing waste and maximizing productivity.

The other options do not accurately reflect the usual yields observed in practice. Yields of 75-90% would suggest a high efficiency that is often not feasible in real-world conditions, while 30-50% would be considered below average for a successful synthesis. Yields in the 80-100% range would imply an exceptional process without losses, which is also unrealistic given the complexities involved in the radiochemistry and logistics of production.