Which age group is most associated with chronic leukemia?

Chronic leukemia is most commonly associated with the elderly population, particularly those aged 65 and older. This association can be attributed to a combination of factors, including the cumulative exposure to environmental risk factors over time, changes in the immune system, and genetic predispositions that may develop with age.

Chronic forms of leukemia, such as chronic lymphocytic leukemia (CLL) and chronic myeloid leukemia (CML), are predominantly diagnosed in older adults. The incidence of these types of leukemia increases significantly with age, reflecting the longer duration during which potential risk factors can exert an effect, as well as aspects of aging that may contribute to alterations in bone marrow and blood cell production.

In contrast, chronic leukemia is less common in children and young adults, where acute leukemias are more frequently diagnosed. Middle-aged adults may also experience cases, but the prevalence is significantly higher in the elderly, making them the group most associated with this condition.