Which of the following conditions is NOT typically associated with memory loss and behavioral changes?

Multiple myeloma is a type of blood cancer that primarily affects plasma cells in the bone marrow, leading to the production of abnormal proteins. The condition is characterized by bone pain, anemia, and infections due to its impact on the immune system. While multiple myeloma can cause cognitive issues indirectly through factors such as anemia or neurological complications, it does not directly result in memory loss and behavioral changes in the way that neurodegenerative diseases do.

In contrast, Alzheimer's disease, frontotemporal dementia, and Pick's disease are all conditions that are directly linked to memory impairment and changes in behavior due to their effects on brain function. Alzheimer's disease primarily involves memory loss, confusion, and changes in personality. Frontotemporal dementia often affects personality, behavior, and executive functions before memory, while Pick's disease, a form of frontotemporal dementia, is specifically associated with significant personality changes and social withdrawal.

Thus, the presence of memory loss and behavioral changes is a defining characteristic of Alzheimer's disease, frontotemporal dementia, and Pick's disease, but not of multiple myeloma, making it the condition that stands apart from the others in this context.