Which term describes Gray Matter FDG Uptake?

Gray matter typically exhibits a significant level of glucose metabolism, which is assessed through fluorodeoxyglucose (FDG) uptake in Positron Emission Tomography (PET) imaging. This characteristic is due to the metabolic demands of neurons, which require glucose as their primary energy source. Given this physiological background, the term "FDG Avid" accurately describes gray matter FDG uptake because it indicates a higher metabolic activity and the presence of increased radiotracer localization in these areas.

The other terms do not appropriately capture the extent of FDG uptake seen in gray matter. For instance, "Minimally FDG Avid" or "Non FDG Avid" suggest a low level of FDG uptake, which is inconsistent with the known behavior of gray matter in the brain. Meanwhile, "Intermediate FDG Avid" implies a moderate level of uptake, which still doesn't fully represent the metabolically active nature of gray matter compared to other tissues. Therefore, "FDG Avid" is the most accurate term to describe the significant uptake of FDG in gray matter.